Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An unconventional NLS is critical for the nuclear import of the influenza A virus nucleoprotein and ribonucleoprotein.

Traffic (Copenhagen, Denmark) - 1 Mar 2005

Cros Jerome F, García-Sastre Adolfo, Palese Peter

Abstract excerpt

Replication of the RNAs of influenza virus occurs in the nucleus of infected cells. The nucleoprotein (NP) has been shown to be important for the import of the viral RNA into the nucleus and has been proposed to contain at least three different nuclear localization signals (NLSs). Here, an import assay in digitonin-permeabilized cells was used to further define the contribution of these NLSs. Mutation of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Active Transport, Cell Nucleus
Share to alpha Karyopherins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Influenza A virus

Share to Nuclear Localization Signals

Share to Nucleocapsid Proteins

Share to Nucleoproteins

Share to Ribonucleoproteins

Share to Viral Core Proteins

Source

Identifiers

PMID: 15702989
DOI: 10.1111/j.1600-0854.2005.00263.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An unconventional NLS is critical for the nuclear import of the influenza A virus nucleoprotein and ribonucleoprotein.PMID 15702989Read ↗

Nuclear and Nucleolar Targeting of Influenza A Virus NS1 Protein: Striking Differences between Different Virus SubtypesSemantic proximity Read ↗

Contributions of two nuclear localization signals of influenza A virus nucleoprotein to viral replication.Semantic proximity Read ↗

Characterization of an Unusual Importin α Binding Motif in the Borna Disease Virus p10 Protein That Directs Nuclear ImportSemantic proximity Read ↗

Contribution of the Nuclear Localization Sequences of Influenza A Nucleoprotein to the Nuclear Import of the Influenza Genome in Infected CellsSemantic proximity Read ↗

Differential Behaviours and Preferential Bindings of Influenza Nucleoproteins on Importins-α.Semantic proximity Read ↗

Identification and characterization of three novel nuclear export signals in the influenza A virus nucleoprotein.Semantic proximity Read ↗

Synergy of two low-affinity NLSs determines the high avidity of influenza A virus nucleoprotein NP for human importin α isoforms.Semantic proximity Read ↗

A classical bipartite nuclear localization signal on Thogoto and influenza A virus nucleoproteins.Semantic proximity Read ↗

Functional identification of multiple nucleocytoplasmic trafficking signals in the broad-spectrum resistance protein RPW8.2.Semantic proximity Read ↗

A novel receptor-mediated nuclear protein import pathway.Semantic proximity Read ↗

Importin α3/Qip1 is involved in multiplication of mutant influenza virus with alanine mutation at amino acid 9 independently of nuclear transport function.Semantic proximity Read ↗

Dominant-negative mutants of importin-beta block multiple pathways of import and export through the nuclear pore complex.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.