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Article

Importin α3/Qip1 is involved in multiplication of mutant influenza virus with alanine mutation at amino acid 9 independently of nuclear transport function.

PloS one - 1 Jan 2013

Sasaki Yutaka, Hagiwara Kyoji, Kakisaka Michinori, Yamada Kazunori, Murakami Tomoyuki, Aida Yoko

Abstract excerpt

The nucleoprotein (NP) of influenza A virus is transported into the nucleus via the classical importin α/β pathway, and proceeds via nuclear localization signals (NLSs) recognized by importin α molecules. Although NP binds to importin α isoforms Rch1, Qip1 and NPI-1, the role of each individual isoform during the nuclear transport of NP and replication of the influenza virus remains unknown. In this study, we...

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Identifiers

PMID: 23383277
DOI: 10.1371/journal.pone.0055765
PMCID: PMC3559588

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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