Article
Anti-apoptotic effect of HCV core gene of genotype 3a in Huh-7 cell line.
Virology journal - 23 Nov 2011
Jahan Shah, Khaliq Saba, Siddiqi Muhammad Hassan, Ijaz Bushra, Ahmad Waqar, Ashfaq Usman A, Hassan Sajida
Abstract excerpt
BACKGROUND: Hepatitis C virus (HCV) Core protein regulates multiple signaling pathways and alters cellular genes expression responsible for HCV induced pathogenesis leading to hepatocellular carcinoma (HCC). Prevalence of HCV genotype 3a associated HCC is higher in Pakistan as compare to the rest of world; however the molecular mechanism behind this is still unclear. This study has been designed to evaluate the...
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