Article
A central resource for accurate allele frequency estimation from pooled DNA genotyped on DNA microarrays.
Nucleic acids research - 8 Feb 2005
Simpson Claire L, Knight Joanne, Butcher Lee M, Hansen Valerie K, Meaburn Emma, Schalkwyk Leonard C, Craig Ian W, Powell John F, Sham Pak C, Al-Chalabi Ammar
Abstract excerpt
Analysing pooled DNA on microarrays is an efficient way to genotype hundreds of individuals for thousands of markers for genome-wide association. Although direct comparison of case and control fluorescence scores is possible, correction for differential hybridization of alleles is important, part...
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