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Article

Alterations in leukocyte function following surgical trauma: differentiation of distinct reaction types and association with tumor necrosis factor gene polymorphisms.

Clinical and diagnostic laboratory immunology - 1 Feb 2005

Majetschak Matthias, Krehmeier Ulrich, Ostroverkh Liljana, Blömeke Brunhilde, Schäfer Michael

Abstract excerpt

Endotoxin-stimulated blood cytokine responses have been widely used to describe compromised host defense mechanisms after trauma. We investigated whether blood cytokine production after endotoxin stimulation is able to define distinct trauma-induced alteration patterns and whether alteration patterns are associated with tumor necrosis factor (TNF) gene polymorphisms. In 48 patients undergoing joint replacement,...

Topics

Aged
Alleles
Arthroplasty, Replacement
Female
Genotype
Humans
Leukocytes
Lymphotoxin-alpha
Male
Polymorphism, Genetic
Tumor Necrosis Factor-alpha

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15699425
DOI: 10.1128/CDLI.12.2.296-303.2005
PMCID: PMC549310

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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