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Article

The TNF (-308A) polymorphism is associated with microchimerism in transfused trauma patients.

Blood - 1 Apr 2008

Gill Ryan M, Lee Tzong-Hae, Utter Garth H, Reed William F, Wen Li, Chafets Dan, Busch Michael P

Abstract excerpt

Microchimerism (MC), defined as the persistence of allogeneic cells at low concentrations, is well documented in transfused trauma patients. We hypothesized that genetic polymorphisms linked to cytokine production could contribute to trauma-induced immune modulation and development of microchimerism after transfusion of trauma patients. We used high-throughput SYBR-green-based genotyping of single nucleotide...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18199828
DOI: 10.1182/blood-2007-08-107144
PMCID: PMC2275039

Genes

TNF
IFNG
TGFB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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