Article
The systemic inflammatory response induced by trauma is reflected by multiple phenotypes of blood neutrophils.
Injury - 1 Dec 2007
Pillay J, Hietbrink F, Koenderman L, Leenen L P H
Abstract excerpt
Secondary morbidity and mortality after trauma are mainly due to a dysfunctional immune system. Severe injury can trigger a systemic inflammatory response, which is characterised by pre-activation or priming of neutrophils in peripheral blood. Signals initiated as result of local tissue damage can further activate these neutrophils leading to post-injury inflammatory complications. Additional trauma caused by...
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