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Article

Association between gene expression biomarkers of immunosuppression and blood transfusion in severely injured polytrauma patients.

Annals of surgery - 1 Apr 2015

Torrance Hew Dt, Brohi Karim, Pearse Rupert M, Mein Charles A, Wozniak Eva, Prowle John R, Hinds Charles J, OʼDwyer Michael J

Abstract excerpt

OBJECTIVE: To explore the hypothesis that blood transfusion contributes to an immunosuppressed phenotype in severely injured patients. BACKGROUND: Despite trauma patients using disproportionately large quantities of blood and blood products, the immunomodulatory effects of blood transfusion in this group are inadequately described. METHODS: A total of 112 ventilated polytrauma patients were recruited. Messenger...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24670848
DOI: 10.1097/SLA.0000000000000653

Genes

GATA3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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