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Article

Genetic association between the APOE*4 allele and Lewy bodies in Alzheimer disease.

Neurology - 8 Feb 2005

Tsuang D W, Wilson R K, Lopez O L, Luedecking-Zimmer E K, Leverenz J B, DeKosky S T, Kamboh M I, Hamilton R L

Abstract excerpt

OBJECTIVE: To explore the association between APOE*4 and pathologically confirmed cases of the Lewy body (LB) variant of Alzheimer disease (AD). METHODS: With use of alpha-synuclein (AS) immunohistochemistry, LBs were detected in 74 of 131 (56.5%) of the AD + LB cases; the remaining 57 cases (43.5%) did not have LBs. RESULTS: There were no differences in gender or age between Caucasian subjects with AD + LB or AD...

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Source

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Identifiers

PMID: 15699383
DOI: 10.1212/01.WNL.0000150892.81839.D1
PMCID: PMC1487185

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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