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Article

APOE ϵ4 Increases Risk for Dementia in Pure Synucleinopathies

19 Nov 2012

Abstract excerpt

OBJECTIVE: To test for an association between the apolipoprotein E (APOE) ϵ4 allele and dementias with synucleinopathy. DESIGN: Genetic case-control association study. SETTING: Academic research. PATIENTS: Autopsied subjects were classified into 5 categories: dementia with high-level Alzheimer disease (AD) neuropathologic changes (NCs) but without Lewy body disease (LBD) NCs (AD group; n=244), dementia with...

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PMID: 23407718
DOI: 10.1001/jamaneurol.2013.600

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