Article
Apolipoprotein E4 frequencies in a Japanese population with Alzheimer's disease and dementia with Lewy bodies.
PloS one - 28 Apr 2011
Kobayashi Seiju, Tateno Masaru, Park Tae Woo, Utsumi Kumiko, Sohma Hitoshi, Ito Yoichi M, Kokai Yasuo, Saito Toshikazu
Abstract excerpt
BACKGROUND: The apolipoprotein E (APOE) ε4 allele has been reported to be a risk factor for Alzheimer's disease (AD) and dementia with Lewy bodies (DLB). Previous neuropathological studies have demonstrated similar frequencies of the APOE ε4 allele in AD and DLB. However, the few ante-mortem studies on APOE allele frequencies in DLB have shown lower frequencies than post-mortem studies. One reason for this may be...
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