Article
[Mutations of mitochondrial 12S rRNA gene in type 2 diabetes].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Oct 2001
Yu Y, Shi J, Shang S, Teng X, Li W, Wu Z
Abstract excerpt
OBJECTIVE: To investigate mutations at points 1310, 1438 and 1442 of mitochondrial 12S rRNA gene in Chinese type 2 diabetes and screen for new mutations associated with type 2 diabetes in this area. METHODS: The mitochondrial DNAs (mtDNAs) of 86 patients with type 2 diabetes and those of 70 normal controls were analyzed using PCR-SSCP and PCR product direct sequencing technique. RESULTS: One patient was found...
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