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Article

Genetic variants of human beta-defensin-1 and chronic obstructive pulmonary disease.

Biochemical and biophysical research communications - 15 Feb 2002

Matsushita Ikumi, Hasegawa Kyoko, Nakata Koh, Yasuda Kazuki, Tokunaga Katsushi, Keicho Naoto

Abstract excerpt

Chronic obstructive pulmonary disease (COPD) is due to interactions between cigarette smoke exposure and other risk factors. Genetic variations of human beta-defensin-1 (hBD-1), an endogenous antimicrobial peptide in the airway, were investigated in 60 patients and 213 healthy volunteers by single-strand conformation and restriction fragment length polymorphism analysis and DNA sequencing. Four nucleotide...

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Identifiers

PMID: 11829455
DOI: 10.1006/bbrc.2002.6395

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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