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Article

Role of tyrosine phosphorylation-dephosphorylation in copy number control of the yeast plasmid 2 micron circle.

Cellular & molecular biology research - 1 Jan 1994

Saxena P, Whang I, Lee J, Lee J, Voziyanov Y, Mendoza V, Jayaram M

Abstract excerpt

A key feature of the copy control in the 2 micron circle plasmid of Saccharomyces cerevisiae is its ability to amplify when the copy number drops below the steady state value. The Flp protein encoded by the plasmid is an essential component of the amplification mechanism. A central regulatory event in amplification involves the phosphorylation/dephosphorylation of Tyr-343 of Flp. Tyrosine phosphorylation is...

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PMID: 7874198

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Research trail→

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Role of tyrosine phosphorylation-dephosphorylation in copy number control of the yeast plasmid 2 micron circle.PMID 7874198Read ↗

A new system for amplifying 2 microns plasmid copy number in Saccharomyces cerevisiae.Semantic proximity Read ↗

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The mcm2 mutation of yeast affects replication, rather than segregation or amplification of the two micron plasmid.Semantic proximity Read ↗

The 2 microm plasmid causes cell death in Saccharomyces cerevisiae with a mutation in Ulp1 protease.Semantic proximity Read ↗

RSC2, encoding a component of the RSC nucleosome remodeling complex, is essential for 2 microm plasmid maintenance in Saccharomyces cerevisiae.Semantic proximity Read ↗

TrfA dimers play a role in copy-number control of RK2 replication.Semantic proximity Read ↗

Sequence diversity of yeast 2 microns RAF gene and its co-evolution with STB and REP1.Semantic proximity Read ↗

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