A systematic high-throughput screen of a yeast deletion collection for mutants defective in PHO5 regulation.

doi:10.1534/genetics.104.038695

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Article

A systematic high-throughput screen of a yeast deletion collection for mutants defective in PHO5 regulation.

Genetics - 1 Apr 2005

Huang Sidong, O'Shea Erin K

Abstract excerpt

In response to phosphate limitation, Saccharomyces cerevisiae induces transcription of a set of genes important for survival. One of these genes is PHO5, which encodes a secreted acid phosphatase. A phosphate-responsive signal transduction pathway (the PHO pathway) mediates this response through three central components: a cyclin-dependent kinase (CDK), Pho85; a cyclin, Pho80; and a CDK inhibitor (CKI), Pho81....

Topics

Acid Phosphatase
Adenosine Kinase
Adenylate Kinase
Automation
Bacterial Proteins
Culture Media
Cyclin-Dependent Kinases
Cyclins
Gene Deletion
Gene Expression Regulation, Fungal
Genes, Fungal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Techniques

Genotype

Luminescent Proteins

Models, Biological

Mutation

Phenotype

Phosphates

Source

Open in PubMed Open full text

Identifiers

PMID: 15695358
DOI: 10.1534/genetics.104.038695
PMCID: PMC1360160

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-15695358-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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