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Article

A systematic high-throughput screen of a yeast deletion collection for mutants defective in PHO5 regulation.

Genetics - 1 Apr 2005

Huang Sidong, O'Shea Erin K

Abstract excerpt

In response to phosphate limitation, Saccharomyces cerevisiae induces transcription of a set of genes important for survival. One of these genes is PHO5, which encodes a secreted acid phosphatase. A phosphate-responsive signal transduction pathway (the PHO pathway) mediates this response through three central components: a cyclin-dependent kinase (CDK), Pho85; a cyclin, Pho80; and a CDK inhibitor (CKI), Pho81....

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Identifiers

PMID: 15695358
DOI: 10.1534/genetics.104.038695
PMCID: PMC1360160

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A systematic high-throughput screen of a yeast deletion collection for mutants defective in PHO5 regulation.PMID 15695358Read ↗

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