Article
Interaction of Saccharomyces cerevisiae Pho2 with Pho4 increases the accessibility of the activation domain of Pho4.
Molecular & general genetics : MGG - 12 Jun 1996
Shao D, Creasy C L, Bergman L W
Abstract excerpt
In Saccharomyces cerevisiae, expression of acid phosphatase, encoded by the PHO5 gene, requires two positive regulatory factors, Pho4 and Pho2 (also called Bas2 or Grf10). Using GAL4-PHO4 fusions, we demonstrate that a functional interaction between these two proteins is necessary for transcripti...
Topics
- Amino Acid Sequence
- Conserved Sequence
- DNA-Binding Proteins
- Fungal Proteins
- Helix-Loop-Helix Motifs
- Homeodomain Proteins
- Membrane Transport Proteins
- Models, Genetic
- Molecular Sequence Data
- Mutation
- Phosphate Transport Proteins
- Recombinant Fusion Proteins
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Sequence Deletion
- Trans-Activators
- Transcription Factors
- Transcriptional Activation