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Article

High plasma interleukin-18 levels mark the acute phase of hepatitis C virus infection.

The Journal of infectious diseases - 1 Dec 2011

Chattergoon Michael A, Levine Jordana S, Latanich Rachel, Osburn William O, Thomas David L, Cox Andrea L

Abstract excerpt

BACKGROUND: Proinflammatory cytokines play a critical role in antiviral immune responses. Large-scale genome studies have found correlations between single-nucleotide polymorphisms (SNPs) in the interleukin (IL) 18 promoter and spontaneous control of hepatitis C virus (HCV), suggesting a role in clearance. METHODS: Plasma IL-18, IL-1β, IL-6, IL-8, IL-12, interferon-γ, tumor necrosis factor-α, alanine...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21984735
DOI: 10.1093/infdis/jir642
PMCID: PMC3203233

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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