Article
Interferon-γ and Interleukin-10 Gene Polymorphisms are not Predictors of Chronic Hepatitis C (Genotype-4) Disease Progression.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2015
Bahgat Nermine Ahmed, Kamal Manal Mohamed, Abdelaziz Ashraf Omar, Mohye Mohamed Ahmed, Shousha Hend Ibrahim, ahmed Mae Mohamed, Elbaz Tamer Mahmoud, Nabil Mohamed Mahmoud
Abstract excerpt
Immunoregulatory cytokines have an influence on hepatitis C virus (HCV) infection outcome. This study aimed to determine whether single nucleotide polymorphisms (SNP) in IFN- γ and IL-10 genes are associated with susceptibility and/or are markers of prognosis regarding chronic hepatitis C outcomes. IFN γ (+874T/A) and IL-10 (-1082G/A) genotypes were determined in 75 HCV genotype 4 patients with different disease...
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