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Article

[Structure-function relations of glycoprotein hormone receptors and their medical applications].

Bulletin et memoires de l'Academie royale de medecine de Belgique - 1 Jan 2004

Costagliola S

Abstract excerpt

The Thyrotropin receptor (TSHr), like the other members of glycoprotein hormone receptors (GPHR) family (LH/CG and FSH receptors), presents a bipartite structure, with a carboxyl-terminal serpentine region implicated in the transmission of the signal activation and a large extracellular domain (ECD) responsible of the hormone binding with a high affinity. This asks the question of the mechanism implicated in the...

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Identifiers

PMID: 15693546

Genes

ECD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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