Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Disorders caused by mutations of the thyrotropin receptor].

Nihon rinsho. Japanese journal of clinical medicine - 1 Jul 1998

Kosugi S

Abstract excerpt

Since 1993, a number of mutations of the thyrotropin receptor(TSHR) gene causing human diseases have been reported; activating TSHR somatic mutations causing autonomously functioning thyroid nodules, activating TSHR germ-line mutations causing familial non-autoimmune hyperthyroidism, and inactivating TSHR germ-line mutations causing hypothyroidism due to TSH unresponsiveness. Activating TSHR mutations increase...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to TSHR gene
Share to Graves Disease
Share to Hyperthyroidism

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hypothyroidism

Share to Mutation

Share to Receptors, Thyrotropin

Source

Identifiers

PMID: 9702065

Genes

TSHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Disorders caused by mutations of the thyrotropin receptor].PMID 9702065Read ↗

Thyrotropin receptor mutations as a tool to understand thyrotropin receptor action.Semantic proximity Read ↗

Thyrotropin receptor-associated diseases: from adenomata to Graves disease.Semantic proximity Read ↗

[Mutations in thyrotropin receptors as a cause of thyroid dysfunction].Semantic proximity Read ↗

Genetic defects, thyroid growth and malfunctions of the TSHR in pediatric patients.Semantic proximity Read ↗

Activating mutations of the TSH receptor gene cause thyroid diseases.Semantic proximity Read ↗

[Mutations in TSH receptors: pathogenetic significance and clinical relevance].Semantic proximity Read ↗

Mutations of thyrotropin receptor gene.Semantic proximity Read ↗

A novel activating mutation in the thyrotropin receptor gene in an autonomously functioning thyroid nodule developed by a Japanese patient.Semantic proximity Read ↗

The TSH receptor and its role in thyroid disease.Semantic proximity Read ↗

[Activating mutations of the TSH receptor: a synthesis highlighting certain pediatric aspects].Semantic proximity Read ↗

[Non-autoimmune hyperthyroidism and hyperfunctioning thyroid adenomas caused by activating mutation of the thyrotropin receptor].Semantic proximity Read ↗

[Familial congenital hypothyroidism due to loss of function mutation of the thyrotropin receptor (resistance to thyrotropin)].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.