Article
Early carotid atherosclerosis and family history of vascular disease: specific effects on arterial sites have implications for genetic studies.
Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 2003
Jerrard-Dunne Paula, Markus Hugh S, Steckel Donata A, Buehler Alexandra, von Kegler Stefan, Sitzer Matthias
Abstract excerpt
OBJECTIVE: Carotid artery intima-media thickness (IMT) is an intermediate phenotype for atherosclerosis. In a community population (n=5400), we determined whether a parental history of myocardial infarction (MI) or stroke is associated with increased IMT and whether associations differ at specific sites in the carotid arterial tree. METHODS AND RESULTS: Using regression modeling, the proportion of IMT that...
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