Article
The yeast phosphotyrosyl phosphatase activator is part of the Tap42-phosphatase complexes.
Molecular biology of the cell - 1 Apr 2005
Zheng Yin, Jiang Yu
Abstract excerpt
Phosphotyrosyl phosphatase activator PTPA is a type 2A phosphatase regulatory protein that possesses an ability to stimulate the phosphotyrosyl phosphatase activity of PP2A in vitro. In yeast Saccharomyces cerevisiae, PTPA is encoded by two related genes, RRD1 and RRD2, whose products are 38 and 37% identical, respectively, to the mammalian PTPA. Inactivation of either gene renders yeast cells rapamycin...
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