Article
A pair of Sox: distinct and overlapping functions of zebrafish sox9 co-orthologs in craniofacial and pectoral fin development.
Development (Cambridge, England) - 1 Mar 2005
Yan Yi-Lin, Willoughby John, Liu Dong, Crump Justin Gage, Wilson Catherine, Miller Craig T, Singer Amy, Kimmel Charles, Westerfield Monte, Postlethwait John H
Abstract excerpt
Understanding how developmental systems evolve after genome amplification is important for discerning the origins of vertebrate novelties, including neural crest, placodes, cartilage and bone. Sox9 is important for the development of these features, and zebrafish has two co-orthologs of tetrapod SOX9 stemming from an ancient genome duplication event in the lineage of ray-fin fish. We have used a genotype-driven...
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