Article
Neuroblastoma: the result of multistep transformation?
Stem cells (Dayton, Ohio) - 1 Jul 1993
Tonini G P
Abstract excerpt
Genetic and molecular abnormalities, in association with malignant phenotypes, have been previously demonstrated in a variety of human tumors. Although the multistep theory fits well for some cancers such as retinoblastoma and colon carcinoma, for many others it still remains to be proven. Neuroblastoma, a tumor found in pediatric patients, seems to fall into the multistep model. Nonrandom chromosome...
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