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Article

Multiplexed genotyping with sequence-tagged molecular inversion probes.

Nature biotechnology - 1 Jun 2003

Hardenbol Paul, Banér Johan, Jain Maneesh, Nilsson Mats, Namsaraev Eugeni A, Karlin-Neumann George A, Fakhrai-Rad Hossein, Ronaghi Mostafa, Willis Thomas D, Landegren Ulf, Davis Ronald W

Abstract excerpt

We report on the development of molecular inversion probe (MIP) genotyping, an efficient technology for large-scale single nucleotide polymorphism (SNP) analysis. This technique uses MIPs to produce inverted sequences, which undergo a unimolecular rearrangement and are then amplified by PCR using common primers and analyzed using universal sequence tag DNA microarrays, resulting in highly specific genotyping....

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PMID: 12730666
DOI: 10.1038/nbt821

Genes

MIP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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