Article
Genetic polymorphism in sex hormone metabolism and prostate cancer risk.
Genetics and molecular research : GMR - 3 Jul 2015
Ersekerci E, Sofikerim M, Taheri S, Demirtas A, Halis F
Abstract excerpt
We compared single-nucleotide polymorphisms for point mutations in cytochrome P450 genes, including cytochrome P450c17α (CYP17), cytochrome P450 aromatase (CYP19), steroid-5-a-reductase (SRD5A2), and prostate-specific antigen (PSA) involved in androgen and estrogen production. Between January 2008 and January 2010, 90 patients were enrolled in the study. Of these patients, 28 were diagnosed with benign prostatic...
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