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Article

Association of HLA phenotype with primary non-response to recombinant hepatitis B vaccine: a study from north India.

Tropical gastroenterology : official journal of the Digestive Diseases Foundation - 1 Jan 2000

Das Kunal, Gupta R K, Kumar V, Singh Sanjay, Kar P

Abstract excerpt

The hepatitis B vaccine is considered to be highly immunogenic and has a good safety profile. In adults, it has a primary non-response rate of 5%-10%. Causes of nonresponse to hepatitis B vaccine include age, sex, obesity smoking. Certain human leucocyte antigen (HLA) phenotypes have been known to be associated with responsiveness to the vaccine, and found to be different in different ethnic groups, such as...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 15682656

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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