Article
Influence of HLA alleles in response to treatment with pegylated interferon-alpha and ribavirin in patients with chronic hepatitis C.
International journal of immunogenetics - 1 Aug 2012
Marangon A V, Moliterno R A, Sell A M, de Moraes C F V, Grotto R M T, Pardini M C, De Pauli D S, Visentainer J E L, Silva G F
Abstract excerpt
The objective of this study was to analyse the possible role of HLA polymorphism of chronically infected hepatitis C virus patients in the response outcome to treatment with pegylated interferon-alpha plus ribavirin. To that end, 144 Brazilian patients infected only with genotype 1 of the virus were treated with pegylated interferon-alpha at 1.5 μg kg(-1) in conjunction with ribavirin (1000 mg if patient weight...
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