Article
20 μg hepatitis B vaccination reduced the risk of low responsiveness in infants with HLA-II risk genotype of HBsAg positive mothers.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Sept 2018
Cao MengZhuo, Wu YanHua, Wen SiMin, Pan Yuchen, Wang Chong, Zhang Xin, Kong Fei, Lu Ying, Wang Chuan, Niu JunQi, Li Jie, Jiang Jing
Abstract excerpt
Infants born to HBV carrier mothers are persistently at a higher risk for HBV infection. We investigated the association between HLA SNPs and low responsiveness to HBV vaccination, and the differences of immune response in carriers of risk genotypes who received different doses of the vaccination. 1040 infants from the prevention of mother-to-infant transmission of HBV cohort were included. Infants born to HBsAg...
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