Article
Tumor metastasis and the reciprocal regulation of heparanase gene expression by nuclear factor kappa B in human gastric carcinoma tissue.
World journal of gastroenterology - 14 Feb 2005
Cao Hou-Jun, Fang Yong, Zhang Xing, Chen Wen-Jun, Zhou Wen-Peng, Wang Hong, Wang Lin-Bo, Wu Jin-Min
Abstract excerpt
AIM: To investigate whether NF-kappaB is activated in human gastric carcinoma tissues and, if so, to study whether there is any correlation between NF-kappaB activity and heparanase expression in gastric carcinoma. METHODS: NF-kappaB activation was assayed by immunohistochemical staining in formalin-fixed, paraffin-embedded specimens from 45 gastric carcinoma patients. Electrophoretic mobility shift assay (EMSA)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
