Article
Genotoxic consequences associated with oxidative damage in testis of mice subjected to iron intoxication.
Toxicology - 5 Jan 2005
Doreswamy K, Muralidhara
Abstract excerpt
While iron-induced testicular dysfunction has been demonstrated adequately, the mechanism(s) involved and the genotoxic implications are not fully understood. In order to understand the genotoxic effects of iron intoxication, initially induction of oxidative stress response in testis of adult albino mice (CFT-Swiss) was ascertained following administration (i.p.) of acute sub-lethal doses of iron dextran (ID)....
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