Article
Early oxidative stress in testis and epididymal sperm in streptozotocin-induced diabetic mice: its progression and genotoxic consequences.
Reproductive toxicology (Elmsford, N.Y.) - 1 Jun 2007
Shrilatha B, Muralidhara
Abstract excerpt
Experimental induction of diabetes mellitus in animal models using chemical diabetogens is demonstrated to impair testicular function progressively leading to decreased fertility. Although, both steroidogenic and spermatogenic dysfunctions have been reported, the role of oxidative stress mechanism/s has been less understood. We have investigated the induction of oxidative damage during early diabetic phase in...
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