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Article

Nickel-induced oxidative stress in testis of mice: evidence of DNA damage and genotoxic effects.

Journal of andrology - 1 Jan 2000

Doreswamy Kodipura, Shrilatha Balakrishna, Rajeshkumar Thimappa, Muralidhara

Abstract excerpt

Oxidative stress (OS) mechanisms are speculated to play a significant role in nickel-induced toxic effects and their carcinogenic potency. Although nickel-induced oxidative damage in somatic tissues is well demonstrated, evidence of the involvement of a similar mechanism(s) in nickel-induced testicular dysfunction and associated genotoxic effects is scarce. Hence, the present study aimed to investigate the...

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Source

Identifiers

PMID: 15477375
DOI: 10.1002/j.1939-4640.2004.tb03173.x

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LPO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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