Article
Clastogenic effects of hydroquinone: induction of chromosomal aberrations in mouse germ cells.
Mutation research - 1 Aug 1991
Ciranni R, Adler I D
Abstract excerpt
The clastogenic activity of hydroquinone (HQ) in germ cells of male mice was evaluated by analysis of chromosomal aberrations in primary spermatocytes and differentiating spermatogonia. In the first experiment with treated spermatocytes the most sensitive stage of meiotic prophase to aberration induction by HQ was determined. Testicular material was sampled for microscopic analysis of cells in...
Topics
- Animals
- Chromosome Aberrations
- Dose-Response Relationship, Drug
- Hydroquinones
- Male
- Mice
- Mice, Inbred C3H
- Mutagenicity Tests
- Mutation
- Polyploidy
- Spermatocytes
- Spermatogonia
