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Article

Plk1 docking to GRASP65 phosphorylated by Cdk1 suggests a mechanism for Golgi checkpoint signalling.

The EMBO journal - 23 Feb 2005

Preisinger Christian, Körner Roman, Wind Mathias, Lehmann Wolf D, Kopajtich Robert, Barr Francis A

Abstract excerpt

GRASP65, a structural protein of the Golgi apparatus, has been linked to the sensing of Golgi structure and the integration of this information with the control of mitotic entry in the form of a Golgi checkpoint. We show that Cdk1-cyclin B is the major kinase phosphorylating GRASP65 in mitosis, and that phosphorylated GRASP65 interacts with the polo box domain of the polo-like kinase Plk1. GRASP65 is...

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Identifiers

PMID: 15678101
DOI: 10.1038/sj.emboj.7600569
PMCID: PMC549625

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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