Article
Assessment of a systematic expression profiling approach in ENU-induced mouse mutant lines.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jan 2005
Seltmann Matthias, Horsch Marion, Drobyshev Alexei, Chen Yali, de Angelis Martin Hrabé, Beckers Johannes
Abstract excerpt
Comparative genomewide expression profiling is a powerful tool in the effort to annotate the mouse genome with biological function. The systematic analysis of RNA expression data of mouse lines from the Munich ENU mutagenesis screen might support the understanding of the molecular biology of such mutants and provide new insights into mammalian gene function. In a direct comparison of DNA microarray experiments of...
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