Article
A genome-wide search for linkage to allergic rhinitis in Danish sib-pair families.
European journal of human genetics : EJHG - 1 Sept 2012
Kruse Lisbeth Venø, Nyegaard Mette, Christensen Ulla, Møller-Larsen Steffen, Haagerup Annette, Deleuran Mette, Hansen Lars Gudmund, Venø Stine Krogh, Goossens Dirk, Del-Favero Jurgen, Børglum Anders Dupont
Abstract excerpt
Allergic rhinitis (AR) is a complex disorder with a polygenic, multifactorial aetiology. Twin studies have found the genetic contribution to be substantial. We collected and clinically characterised a sample consisting of 127 Danish nuclear families with at least two siblings suffering from AR or allergic conjunctivitis including 540 individuals (286 children and 254 parents). A whole-genome linkage scan, using...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
