Article
Association analysis between hypertension and CYBA, CLCNKB, and KCNMB1 functional polymorphisms in the Japanese population--the Suita Study.
Circulation journal : official journal of the Japanese Circulation Society - 1 Feb 2005
Kokubo Yoshihiro, Iwai Naoharu, Tago Naomi, Inamoto Nozomu, Okayama Akira, Yamawaki Hideyuki, Naraba Hiroaki, Tomoike Hitonobu
Abstract excerpt
BACKGROUND: Reproducibility of results is important for the validity of genetic association studies. Recently, 3 functional polymorphisms, G(-930)A in CYBA, T481S in CLCNKB, and E65K in KCNMB1, were reported to be associated with blood pressure (BP) status and the aim of this study was to confirm those findings using a large cohort representing the general Japanese population. METHODS AND RESULTS: The study...
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