CACNA1C rs1006737 SNP increases the risk of essential hypertension in both Chinese Han and ethnic Russian people of Northeast Asia.

doi:10.1097/MD.0000000000024825

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CACNA1C rs1006737 SNP increases the risk of essential hypertension in both Chinese Han and ethnic Russian people of Northeast Asia.

Medicine - 26 Feb 2021

Zhang Hao, Pushkarev Boris, Zhou Jiexin, Mu Yuyuan, Bolshakova Olga, Shrestha Sandeep, Wang Ningning, Jian Baiyu, Jin Ming, Zhang Keyong, Cong Mingyu, Liu Jicheng, Vitkovsky Yuri, Qiu Changchun

Abstract excerpt

ABSTRACT: Voltage-gated Ca2+ channels play a key role in the regulation of arterial tone and blood pressure. The aim of this study was to determine whether the association of calcium voltage-gated channel subunit alpha1 C (CACNA1C) rs1006737 with essential hypertension (EH) exists in both Chinese Han and ethnic Russian populations of Northeast Asia. We used a case-control study of 2 ethnic groups in the same...

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PMID: 33663102
DOI: 10.1097/MD.0000000000024825
PMCID: PMC7909128

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