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Article

Polymorphisms in the GNB3 and ADD1 genes and blood pressure in a Chinese population.

Human genetics - 1 Aug 2010

Chen Shufeng, Wang Hongwei, Lu Xiangfeng, Liu De-Pei, Chen Jing, Jaquish Cashell E, Rao Dabeeru C, Hixson James E, Kelly Tanika N, Hou Liping, Wang Laiyuan, Huang Jianfeng, Chen Chung-Shiuan, Rice Treva K, Whelton Paul K, He Jiang, Gu Dongfeng

Abstract excerpt

A large proportion of the phenotypic variation in blood pressure (BP) appears to be inherited as a polygenic trait. This study examined the association between 12 single nucleotide polymorphisms (SNPs) in the guanine nucleotide binding protein beta polypeptide 3 (GNB3) and adducin 1 alpha (ADD1) genes and systolic (SBP), diastolic (DBP), and mean arterial (MAP) BP. A total of 3,142 individuals from 636 families...

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Source

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Identifiers

PMID: 20473689
DOI: 10.1007/s00439-010-0834-3
PMCID: PMC9003865

Genes

GNB3
DBP
ADD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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