Article
Carcinogen metabolism genes, red meat and poultry intake, and colorectal cancer risk.
International journal of cancer - 15 Apr 2012
Wang Jun, Joshi Amit D, Corral Román, Siegmund Kimberly D, Marchand Loïc Le, Martinez Maria Elena, Haile Robert W, Ahnen Dennis J, Sandler Robert S, Lance Peter, Stern Mariana C
Abstract excerpt
Diets high in red meat are established risk factors for colorectal cancer (CRC). Carcinogenic compounds generated during meat cooking have been implicated as causal agents. We conducted a family-based case-control study to investigate the association between polymorphisms in carcinogen metabolism genes (CYP1A2 -154A>C, CYP1B1 Leu432Val, CYP2E1 -1054C>T, GSTP1 Ile105Val, PTGS2 5UTR -765, EPHX1 Tyr113His, NAT2...
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