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Article

Depression in Parkinson's disease is related to a genetic polymorphism of the cannabinoid receptor gene (CNR1).

The pharmacogenomics journal - 1 Jan 2005

Barrero F J, Ampuero I, Morales B, Vives F, de Dios Luna Del Castillo J, Hoenicka J, García Yébenes J

Abstract excerpt

Depression is a common symptom in Parkinson's disease (PD) and it is present in up to 40% of the patients. The cause of depression in PD is thought to be related to disturbance of monoamine neurotransmission. The endogenous cannabinoid system mediates different brain processes that play a role in the control of behaviour and emotions. Cannabinoid function may be altered in neuropsychiatry diseases, directly or...

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Identifiers

PMID: 15668727
DOI: 10.1038/sj.tpj.6500301

Genes

CNR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Depression in Parkinson's disease is related to a genetic polymorphism of the cannabinoid receptor gene (CNR1).PMID 15668727Read ↗

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