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Article

Reaction-kinetic parameters of glycidamide as determinants of mutagenic potency.

Mutation research - 7 Feb 2005

Silvari V, Haglund J, Jenssen D, Golding B T, Ehrenberg L, Törnqvist M

Abstract excerpt

Values for reaction-kinetic parameters of electrophiles can be used to predict mutagenic potency. One approach employs the Swain-Scott relationship for comparative kinetic studies of electrophilic agents reacting with nucleophiles. In this way glycidamide (GA), the putatively mutagenic/carcinogenic metabolite of acrylamide, was assessed by determining the rates of reaction with different nucleophiles. The rate...

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Identifiers

PMID: 15668111
DOI: 10.1016/j.mrgentox.2004.11.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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