Article
In vitro studies of the influence of glutathione transferases and epoxide hydrolase on the detoxification of acrylamide and glycidamide in blood.
Mutation research - 7 Feb 2005
Paulsson Birgit, Rannug Agneta, Henderson Alistair P, Golding Bernard T, Törnqvist Margareta, Warholm Margareta
Abstract excerpt
Enzymes involved in the metabolism of xenobiotic substances are often polymorphic in humans. Such genetic polymorphisms may result in inter-individual differences in detoxification of certain chemicals, and as a consequence, possibly affect health-risk assessments. This present work concerns studies of the influence of polymorphic enzymes in the detoxification of acrylamide and its metabolite glycidamide. Enzymes...
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