Article
In vitro studies of the influence of certain enzymes on the detoxification of acrylamide and glycidamide in blood.
Advances in experimental medicine and biology - 1 Jan 2005
Paulsson Birgit, Warholm Margareta, Rannug Agneta, Törnqvist Margareta
Abstract excerpt
Several enzymes involved in the metabolism of xenobiotic substances are polymorphic in humans. Inter-individual differences in response to certain chemicals, such as acrylamide, as a result of such genetic polymorphisms might affect health-risk assessments. Detoxification by, for example, conjugation with glutathione (GSH) will decrease the concentration. The dose of the compound and enzymes that enhance the...
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