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Article

Influence of metabolic genotypes on biomarkers of exposure to 1,3-butadiene in humans.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Oct 2002

Fustinoni Silvia, Soleo Leonardo, Warholm Margareta, Begemann Petra, Rannug Agneta, Neumann Hans-G, Swenberg James A, Vimercati Luigi, Colombi Antonio

Abstract excerpt

Carcinogenicity of 1,3-butadiene (BD) has been linked to its metabolic activation of genotoxic epoxides. The inherited variations in the activity of BD-metabolizing enzymes may be responsible for individual differences that modulate the effects of BD exposure. In this study, 40 Italian subjects (...

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Source

Identifiers

PMID: 12376511

Genes

GSTM1
GSTT1
GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12376511-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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