Article
Transient idling of posttermination ribosomes ready to reinitiate protein synthesis.
Biochimie - 1 Dec 2004
Karamyshev Andrey L, Karamysheva Zemfira N, Yamami Tohru, Ito Koichi, Nakamura Yoshikazu
Abstract excerpt
The fate of ribosomes between termination and initiation during protein synthesis is very basic, yet poorly understood. Here we found that translational reinitiation of the alkaline phosphatase gene occurs in Escherichia coli from an internal methionine codon when the authentic translation is prematurely terminated at a nonsense codon that is within seven codons upstream of the reinitiation codon (which we refer...
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