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Article

<i>MDR1</i> and <i>MRP1</i> gene expression are independent predictors for treatment outcome in adult acute myeloid leukaemia

24 Jan 2005

Abstract excerpt

Multi drug resistance (MDR) is a major obstacle for cancer therapy. The three major candidates accounting for the development of MDR in acute myeloid leukaemia (AML) are multi drug resistance gene (MDR1), multi drug resistance-related protein gene (MRP1) and lung resistance protein gene (LRP). So far, the differential impact of resistance gene expression on treatment outcome in AML is not clear. Therefore, we...

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PMID: 15667534
DOI: 10.1111/j.1365-2141.2004.05319.x

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