Article
The melanocortin pathway: effects of voluntary exercise on the melanocortin-4 receptor knockout mice and ACTH(1-24) ligand structure activity relationships at the melanocortin-2 receptor.
Endocrine research - 1 Nov 2004
Haskell-Luevano C, Todorovic A, Gridley K, Sorenson N, Irani B, Xiang Z
Abstract excerpt
The melanocortin pathway consists of endogenous agonists, antagonists, G-protein coupled receptors, and ancillary proteins that mediate the function of the endogenous antagonists. The melanocortin-4 receptor (MC4R) is involved in the regulation of obesity and the melanocortin-2 receptor (MC2R) is involved in the regulation of steroidogenesis. Herein, we present the effects of voluntary exercise on the MC4R...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.