Article
Distributed robustness versus redundancy as causes of mutational robustness.
BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Feb 2005
Wagner Andreas
Abstract excerpt
A biological system is robust to mutations if it continues to function after genetic changes in its parts. Such robustness is pervasive on different levels of biological organization, from macromolecules to genetic networks and whole organisms. I here ask which of two possible causes of such robustness are more important on a genome-wide scale, for systems whose parts are genes, such as metabolic and genetic...
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